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A coalition of organizations representing community pharmacies and pharmacists, pharmacy benefit managers (PBM), health care distributors, and generic pharmaceutical manufacturers urged the Senate to deliver an essential remedy this year to the pending pharmacy Medicaid reimbursement cuts scheduled for January 2008.

The associations and professional societies sent letters to all members of the U.S. Senate to urge passage of Senate Finance Committee Chairman Max Baucus’ (D-MT) Fair Medicaid Drug Payment Act, S. 1951. (Content Read …)

Advances in materials processing - technologies that include micromachining, nanoprocessing and structured film forming - are creating new devices and new opportunities for minimally invasive medicine. These advances have led to the development and introduction of devices that employ very small needles - microneedles - that can deliver drugs or sample analyte by mechanically perforating the outer skin layer. (Content Read …)

genOway, a biotechnology company specialized in the development of genetically modified research models for the biopharmaceutical industry today announces the launching of its catalogue activity, based on the development and supply of standardized tools.

This offer of animal models developed by genOway’s R&D teams or via the acquisition of exclusive and non-exclusive licenses from prestigious academic laboratories such as Yale University (Connecticut), the Hubrecht Institute (Netherlands), and the University of Michigan is based on the supply of ready-for-use tools selectable from the catalogue. (Content Read …)

While consumers and pharmacists are well aware that prescription drug interactions can be dangerous, the fact that each person’s genetic makeup can render certain drugs dangerous or even deadly is not widely recognized.

Students in Purdue University’s Department of Computer and Information Technology are working to develop an information-management tool that could give pharmacists instant access to patients’ genetic profile, making it possible to quickly determine the proper medicine dosage or if the drug cannot be tolerated by the patient. (Content Read …)

The National Rural Health Association (NRHA) has endorsed three legislative solutions in the U.S. House of Representatives and Senate addressing major challenges facing community pharmacies, which are often located in rural communities where patients have limited health care options. The bills NRHA supports remove impediments to the financial viability of community pharmacies who endure slow reimbursement of Medicare Part D claims, pending cuts to Medicaid generic prescription drugs, and an inability to effectively bargain for fair contracts with the pharmacy benefit managers (PBMs) who administer prescription drug plans. (Content Read …)

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Dementia and Comorbidities: An Overview of Diagnosis and Management

Keith A. Swanson, PharmD, CGP

Ryan M. Carnahan, PharmD, MS, BCPP

The term “dementia” describes various neurodegenerative disorders that effect cognition, including Alzheimer disease, vascular dementia, and others. This article reviews the diagnosis and management of common types of dementia and comorbidities.

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Antipsychotic Medication Use in the Elderly Patient

Matthew Malone, DO

Ryan M. Carnahan, PharmD, MS, BCPP

Eric C. Kutscher, PharmD, BCPP

The use of antipsychotic medications in the elderly can be very complex and is ever changing. Consideration must be given to not only the physiologic and functional changes normally associated with age but also to the latest data on safety and adverse outcomes associated with using these agents.

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Reviews

A Review of Drug Interactions With Psychiatric Medicines for the Pharmacy Practitioner

Eric C. Kutscher, PharmD, BCPP

Bruce Alexander, PharmD, BCPP

With thousands of potential drug interactions, it is next to impossible to remember them all, especially with many people on multiple prescriptions and over-the-counter medications. With the increasing use of psychiatric medicines in the general population, drug interactions may occur without recognition or warning.

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Corticosteroid- and Anabolic Steroid—Induced Mental Status Disturbances

Paul J. Perry, PhD, BCPP, FCCP

Corticosteroids and anabolic steroids can induce remarkably similar presentations in the mental status changes that they precipitate. Most individuals demonstrate affect and mood changes consistent with patients diagnosed with either bipolar or unipolar affective disorder. In addition, affective changes can be accompanied by delusions in the minority of subjects.

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Possible Increase in Liver Enzymes Secondary to Atorvastatin and Black Cohosh Administration

Nima M. Patel, PharmD, BCPS

Ramona M. Derkits, PharmD

Introduction: Since the publication of the Women’s Health Initiative (WHI) trials, there has been a decline in the use of hormonal replacement therapy (HRT). The risks outweighed the benefits in the WHI trials, and therefore women are seeking alternative treatments including herbal remedies to HRT for mitigation of postmenopausal conditions.

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